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Supplements

Cut through the supplement hype. Evidence-graded recommendations for creatine, vitamin D, magnesium, omega-3s, and more — with dosing and timing.

Protocols

13

Avg. Evidence

3.7/5

Free

1

Beginner

10

Intermediate

3

Advanced

0

Supplements Protocols

13 of 13

Wellness education only. Review each protocol's caveats, contraindications, and source notes before changing your routine.

beginner

Creatine Monohydrate

3-5g daily of the most researched supplement in sports science. Benefits extend beyond muscle to cognition, bone health, and potentially neuroprotection.

EvidenceVery Strong
1 min/day4-8 weeks1 source1 caveat

Caveat for Creatine Monohydrate: Review first: Severe kidney disease (consult nephrologist)

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beginner

Vitamin D3 + K2

2,000-5,000 IU vitamin D3 daily with K2 (MK-7). Most people are deficient, and optimal levels (40-60 ng/mL) support immune function, bone health, and mood.

EvidenceStrong
1 min/day3-6 months1 source2 caveats

Caveat for Vitamin D3 + K2: Review first: Hypercalcemia

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beginner

Magnesium (Glycinate/Threonate)

200-400mg elemental magnesium daily. Half the population is deficient in this mineral involved in 300+ enzymatic processes including sleep, muscle function, and mood.

EvidenceStrong
1 min/day2-4 weeks1 source2 caveats

Caveat for Magnesium (Glycinate/Threonate): Review first: Kidney disease

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beginner

Foundational Supplement Stack

The essentials: D3+K2, Magnesium, Omega-3, and Creatine. These four address the most widespread deficiencies with the strongest evidence bases.

EvidenceStrong
5 min/day3-6 months1 source1 caveat

Caveat for Foundational Supplement Stack: Review first: See individual supplement entries for specific contraindications

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intermediate

Berberine for Metabolic Health

Berberine (500mg 2-3x/day with meals) activates AMPK and reduces blood glucose comparably to metformin. Strong evidence for improving fasting glucose, HbA1c, and lipids.

EvidenceStrong
2 min/day8-12 weeks1 source3 caveats

Caveat for Berberine for Metabolic Health: Review first: Pregnancy and breastfeeding

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intermediate

Iron and Ferritin Screening

Screen ferritin before supplementing iron. Low ferritin can contribute to fatigue, particularly in menstruating women, but iron should be guided by labs and clinician review.

EvidenceStrong
Lab booking plus 5 min/day if supplementing8-12 weeks when correcting deficiency2 sources4 caveats

Caveat for Iron and Ferritin Screening: Review first: Hemochromatosis

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beginner

Psyllium Fiber Add-On

Use low-dose psyllium as a fiber bridge when food-based fiber intake is not yet consistent.

EvidenceStrong
2 min/day4 weeks1 source3 caveats

Caveat for Psyllium Fiber Add-On: Review first: Swallowing difficulty

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beginner

Vitamin B12 for Plant-Based Diets

Use a reliable B12 source or clinician-guided supplement strategy if you eat little or no animal food.

EvidenceStrong
2 min8-12 weeks1 source1 caveat

Caveat for Vitamin B12 for Plant-Based Diets: Review first: Known B12 deficiency symptoms requiring medical evaluation

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beginner

Ashwagandha (KSM-66)

300-600mg KSM-66 ashwagandha daily. Clinical trials show reduced cortisol (~30%), improved sleep quality, and modest testosterone increases.

EvidenceModerate
1 min/day4-8 weeks1 source3 caveats

Caveat for Ashwagandha (KSM-66): Review first: Thyroid conditions (ashwagandha may raise thyroid hormones)

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beginner

Lion's Mane for Cognition

Lion's Mane mushroom (500-3000mg/day) stimulates NGF production and has shown cognitive improvements in mild cognitive impairment trials. Active compounds: hericenones and erinacines.

EvidenceModerate
2 min/day8-16 weeks1 source3 caveats

Caveat for Lion's Mane for Cognition: Review first: Mushroom allergies

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beginner

Apigenin for Sleep and Relaxation

50mg apigenin before bed modulates GABA-A receptors for mild, clean sedation. Found naturally in chamomile. Also inhibits CD38 enzyme, potentially preserving NAD+ levels.

EvidenceModerate
2 min/day2-4 weeks1 source2 caveats

Caveat for Apigenin for Sleep and Relaxation: Review first: Pregnant women (apigenin has mild estrogenic activity)

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intermediate

Beetroot Nitrate Trial

Test beetroot juice or nitrate-rich foods before endurance sessions or as a blood-pressure-support habit.

EvidenceModerate
5 min/session2 weeks1 source3 caveats

Caveat for Beetroot Nitrate Trial: Review first: Kidney stone history

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beginner
Free

Supplement Pause Audit

Audit your supplement stack by pausing non-essential additions one at a time and keeping only clear winners.

EvidenceModerate
10 min/month1 month1 source1 caveat

Caveat for Supplement Pause Audit: Review first: Do not pause prescribed medication or clinician-directed supplements without medical guidance

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