Supplements
Cut through the supplement hype. Evidence-graded recommendations for creatine, vitamin D, magnesium, omega-3s, and more — with dosing and timing.
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Supplements Protocols
13 of 13Wellness education only. Review each protocol's caveats, contraindications, and source notes before changing your routine.
Creatine Monohydrate
3-5g daily of the most researched supplement in sports science. Benefits extend beyond muscle to cognition, bone health, and potentially neuroprotection.
Caveat for Creatine Monohydrate: Review first: Severe kidney disease (consult nephrologist)
Vitamin D3 + K2
2,000-5,000 IU vitamin D3 daily with K2 (MK-7). Most people are deficient, and optimal levels (40-60 ng/mL) support immune function, bone health, and mood.
Caveat for Vitamin D3 + K2: Review first: Hypercalcemia
Magnesium (Glycinate/Threonate)
200-400mg elemental magnesium daily. Half the population is deficient in this mineral involved in 300+ enzymatic processes including sleep, muscle function, and mood.
Caveat for Magnesium (Glycinate/Threonate): Review first: Kidney disease
Foundational Supplement Stack
The essentials: D3+K2, Magnesium, Omega-3, and Creatine. These four address the most widespread deficiencies with the strongest evidence bases.
Caveat for Foundational Supplement Stack: Review first: See individual supplement entries for specific contraindications
Berberine for Metabolic Health
Berberine (500mg 2-3x/day with meals) activates AMPK and reduces blood glucose comparably to metformin. Strong evidence for improving fasting glucose, HbA1c, and lipids.
Caveat for Berberine for Metabolic Health: Review first: Pregnancy and breastfeeding
Iron and Ferritin Screening
Screen ferritin before supplementing iron. Low ferritin can contribute to fatigue, particularly in menstruating women, but iron should be guided by labs and clinician review.
Caveat for Iron and Ferritin Screening: Review first: Hemochromatosis
Psyllium Fiber Add-On
Use low-dose psyllium as a fiber bridge when food-based fiber intake is not yet consistent.
Caveat for Psyllium Fiber Add-On: Review first: Swallowing difficulty
Vitamin B12 for Plant-Based Diets
Use a reliable B12 source or clinician-guided supplement strategy if you eat little or no animal food.
Caveat for Vitamin B12 for Plant-Based Diets: Review first: Known B12 deficiency symptoms requiring medical evaluation
Ashwagandha (KSM-66)
300-600mg KSM-66 ashwagandha daily. Clinical trials show reduced cortisol (~30%), improved sleep quality, and modest testosterone increases.
Caveat for Ashwagandha (KSM-66): Review first: Thyroid conditions (ashwagandha may raise thyroid hormones)
Lion's Mane for Cognition
Lion's Mane mushroom (500-3000mg/day) stimulates NGF production and has shown cognitive improvements in mild cognitive impairment trials. Active compounds: hericenones and erinacines.
Caveat for Lion's Mane for Cognition: Review first: Mushroom allergies
Apigenin for Sleep and Relaxation
50mg apigenin before bed modulates GABA-A receptors for mild, clean sedation. Found naturally in chamomile. Also inhibits CD38 enzyme, potentially preserving NAD+ levels.
Caveat for Apigenin for Sleep and Relaxation: Review first: Pregnant women (apigenin has mild estrogenic activity)
Beetroot Nitrate Trial
Test beetroot juice or nitrate-rich foods before endurance sessions or as a blood-pressure-support habit.
Caveat for Beetroot Nitrate Trial: Review first: Kidney stone history
Supplement Pause Audit
Audit your supplement stack by pausing non-essential additions one at a time and keeping only clear winners.
Caveat for Supplement Pause Audit: Review first: Do not pause prescribed medication or clinician-directed supplements without medical guidance